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Cagrilintide: A long-acting amylin analog for the treatment of obesity

Amgen's MariTide Phase 2 showed no weight loss plateau at 52 weeks (Nov 2024): The absence of a weight loss plateau effect which both semaglutide and tirzepatide display would be a clinically meaningful differentiation if confirmed in Phase 3, potentially enabling greater sustained weight loss

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Adaptive responses of neuronal mitochondria to bioenergetic challenges: Roles in neuroplasticity and disease resistance