LBP Polyclonal Antibody, 50ul Antisense Oligonucleotides non-receptor type 22 is a

non-receptor type 22 is a lymphoid-specific intracellular phosphatase that associates with the molecular adapter protein CBL and may be involved in regulating CBL function in the T-cell receptor signaling pathway

Mutations in this gene cause X-linked severe combined immunodeficiency (XSCID)

Induces cell cycle arrest and mediates apoptosis by caspase activation and in p53-independent manner

This gene encodes a four transmembrane protein that is a member of the zinc finger DHHC domain-containing protein family

Among its related pathways are Fatty Acyl-CoA Biosynthesis andMetabolism

LBP Polyclonal Antibody, 50ul Antisense Oligonucleotides non-receptor type 22 is aThe protein encoded by LBP is involved in the acute phase immunologic response to gram negative bacterial infections. Gram negative bacteria contain a glycolipid, lipopolysaccharide (LPS), on their outer cell wall. Together with bactericidal permeability increasing protein (BPI), the encoded protein binds LPS and interacts with the CD14 receptor, probably playing a role in regulating LPS dependent monocyte responses. Studies in mice suggest that the