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(2017) Nature 546 : 312-315 PubMed: 28514449 Search on PubMed DOI: Primary Citation Related Structures: 5VEW, 5VEX PubMed Abstract: The glucagon-like peptide-1 receptor (GLP-1R) and the glucagon receptor (GCGR) are members of the secretin-like class B family of G-protein-coupled receptors (GPCRs) and have opposing physiological roles in insulin release and glucose homeostasis