Tamibarotene - CAS# 94497-51-5 oxifen citrate specific and brain-penetrant Lysine Specific

specific and brain-penetrant Lysine Specific Demethylase-1 (LSD1) inhibitor

InChi: InChI=1S/C14H6O8/c15-5-1-3-7-8-4(14(20)22-11(7)9(5)17)2-6(16)10(18)12(8)21-13(3)19/h1-2

functioning as an inhibitor of matrix metalloproteinases

Leuprolide acetate is the acetate salt of a synthetic nonapeptide analogue of gonadotropin-releasing hormone

[Epub ahead of print] PubMed PMID: 27364361

Tamibarotene - CAS# 94497-51-5 oxifen citrate specific and brain-penetrant Lysine SpecificTamibarotene, also known as SY 1425, is an orally active, synthetic retinoid, developed to overcome all trans retinoic acid (ATRA) resistance, with potential antineoplastic activity. As a specific retinoic acid receptor (RAR) alpha beta agonist, tamibarotene is approximately ten times more potent than ATRA in inducing cell differentiation and apoptosis in HL 60 (human promyelocytic leukemia) cell lines in vitro. Due to a lower affinity for cellular