Tuberin(Phospho Tyr1571) Polyclonal Antibody, 20ul Rotator forming tight complexes with papain

forming tight complexes with papain and the cathepsins B

It also functions as a transcriptional repressor of type I collagen genes

The encoded protein contains a highly conserved J domain of about 70 amino acids with a characteristic His-Pro-Asp (HPD) motif and may regulate the activity of binding immunoglobulin protein by stimulating ATPase activity

Inhibited by HIV-1 Nef

Neurotrimin is closely linked to a related family member

Tuberin(Phospho Tyr1571) Polyclonal Antibody, 20ul Rotator forming tight complexes with papainMutations in this gene lead to tuberous sclerosis complex. Its gene product is believed to be a tumor suppressor and is able to stimulate specific GTPases. The protein associates with hamartin in a cytosolic complex, possibly acting as a chaperone for hamartin. Alternative splicing results in multiple transcript variants encoding different isoforms.