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GSH serves as a nucleophilic co-substrate of detoxification enzymes such as glutathione S-transferases (GST) in detoxifying xenobiotics 5,6

If researchers treat dosage as a static recipe, they can miss the reason one protocol produces a clean signal while another produces noise

doi:10.1074/jbc.R113.458810

Approximately 10 5 cells of CO23, CO23MCFG and CO23RFLC strains were serially diluted and spotted onto YPD plates treated or not with 4 mM H 2 O 2 in absence (1) or in presence of GSH precursors 0.02 M glutamate, 0.02 M cysteine, 0.02 M, glycine (2) or with 5 mM BSO (L-buthionine-sulfoximine) (3)

Modified GRF(1-29) without DAC has a shorter duration of action, making it suitable for pulsatile administration that mimics physiological GH secretion patterns when combined with GHRPs