PDHK1(Phospho Tyr243) Rabbit Polyclonal Antibody, 100ul[BT-AP11861] Cryogenic Vials mutations in this gene have

mutations in this gene have been associated with some cases of autosomal dominant craniocervical dystonia

Three phosphofructokinase isozymes exist in humans: muscle

Transcript variants derived from alternative promoter usage and/or alternative splicing exist

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producing phosphatidic acid

PDHK1(Phospho Tyr243) Rabbit Polyclonal Antibody, 100ul[BT-AP11861] Cryogenic Vials mutations in this gene havePyruvate dehydrogenase (PDH) is a mitochondrial multienzyme complex that catalyzes the oxidative decarboxylation of pyruvate and is one of the major enzymes responsible for the regulation of homeostasis of carbohydrate fuels in mammals. The enzymatic activity is regulated by a phosphorylation dephosphorylation cycle. Phosphorylation of PDH by a specific pyruvate dehydrogenase kinase (PDK) results in inactivation. Multiple alternatively spliced