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Then an endocrinologist asked if he'd like to try one of the new class of glucagon-like peptide-1, or GLP-1, drugs that include Wegovy and Mounjaro

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Concomitantly, autophagy was reported to also reduce the hepatocyte apoptosis caused by steatosis and endoplasmic reticulum stress, possibly through the GLP-1RA-stimulated GLP-1R-mediated activation of the EB transcription factor of the autophagy-lysosome pathway, thus reducing the accumulation of liver lipids (201)