mTOR(Phospho Thr2446) Polyclonal Antibody, 20ul Roller Bottles Several alternatively spliced transcript variant

Several alternatively spliced transcript variant

the major process by which intracellular components are targeted to lysosomes for degradation

It can also modulate cell susceptibility to p53-dependent apoptosis by inhibiting calpain activity

The encoded protein shares a high level of similarity to the rat homolog| and contains 3 C2 domains and a diacylglycerol-binding C1 domain

Four alternatively spliced transcript variants encoding distinct isoforms have been reported

mTOR(Phospho Thr2446) Polyclonal Antibody, 20ul Roller Bottles Several alternatively spliced transcript variantThe protein encoded by this gene belongs to a family of phosphatidylinositol kinase related kinases. These kinases mediate cellular responses to stresses such as DNA damage and nutrient deprivation. This protein acts as the target for the cell cycle arrest and immunosuppressive effects of the FKBP12 rapamycin complex. The ANGPTL7 gene is located in an intron of this gene.