PEA-15 Polyclonal Antibody, 50ul[BT-AP07044] Stepper and lowest expression in pancreas
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PEA-15 Polyclonal Antibody, 50ul[BT-AP07044] Stepper and lowest expression in pancreasPEA15 (phosphoprotein enriched in astrocytes 15) encodes a death effector domain containing protein that functions as a negative regulator of apoptosis. The encoded protein is an endogenous substrate for protein kinase C. This protein is also overexpressed in type 2 diabetes mellitus, where it may contribute to insulin resistance in glucose uptake. Alternative splicing results in multiple transcript variants.
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