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PEA-15 Polyclonal Antibody, 50ul[BT-AP07044] Stepper and lowest expression in pancreas

SKU: 48852137066

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PLN162.00 PLN203.00

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PEA-15 Polyclonal Antibody, 50ul[BT-AP07044] Stepper and lowest expression in pancreasPEA15 (phosphoprotein enriched in astrocytes 15) encodes a death effector domain containing protein that functions as a negative regulator of apoptosis. The encoded protein is an endogenous substrate for protein kinase C. This protein is also overexpressed in type 2 diabetes mellitus, where it may contribute to insulin resistance in glucose uptake. Alternative splicing results in multiple transcript variants.

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Description

and lowest expression in pancreas

This protein unwinds double-stranded RNA| folds single-stranded RNA| and may play important roles in ribosomal RNA biogenesis| RNA editing| RNA transport| and general transcription

Transcription factor GATA-4 is thought to regulate genes involved in embryogenesis and in myocardial differentiation and function

This protein regulates the activity of many immediate-early genes

which activates other proenzymes including chymotrypsinogen and procarboxypeptidases

PEA-15 Polyclonal Antibody, 50ul[BT-AP07044] Stepper and lowest expression in pancreasPEA15 (phosphoprotein enriched in astrocytes 15) encodes a death effector domain containing protein that functions as a negative regulator of apoptosis. The encoded protein is an endogenous substrate for protein kinase C. This protein is also overexpressed in type 2 diabetes mellitus, where it may contribute to insulin resistance in glucose uptake. Alternative splicing results in multiple transcript variants.

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