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Gab 2 Polyclonal Antibody, 50ul[BT-AP03411] Pipette Micro Tips The protein encoded by this

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Gab 2 Polyclonal Antibody, 50ul[BT-AP03411] Pipette Micro Tips The protein encoded by thisGAB2 (GRB2 associated binding protein 2) is a member of the GRB2 associated binding protein (GAB) gene family. These proteins contain pleckstrin homology (PH) domain, and bind SHP2 tyrosine phosphatase and GRB2 adapter protein. They act as adapters for transmitting various signals in response to stimuli through cytokine and growth factor receptors, and T and B cell antigen receptors. The protein encoded by GAB2 is the principal activator of

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Description

The protein encoded by this gene is closely related to STAM| an adaptor protein involved in the downstream signaling of cytokine receptors| both of which contain a SH3 domain and the immunoreceptor tyrosine-based activation motif (ITAM)

1 and can hold up to 24 Ø10mm test tubes

KPNA2 protein interacts with the NLSs of DNA helicase Q1 and SV40 T antigen and may be involved in the nuclear transport of proteins

The protein encoded by this gene resides in the golgi| and constitutes one of the 8 subunits of the conserved oligomeric Golgi (COG) complex| which is required for normal golgi morphology and localization

In various human cancers

Gab 2 Polyclonal Antibody, 50ul[BT-AP03411] Pipette Micro Tips The protein encoded by thisGAB2 (GRB2 associated binding protein 2) is a member of the GRB2 associated binding protein (GAB) gene family. These proteins contain pleckstrin homology (PH) domain, and bind SHP2 tyrosine phosphatase and GRB2 adapter protein. They act as adapters for transmitting various signals in response to stimuli through cytokine and growth factor receptors, and T and B cell antigen receptors. The protein encoded by GAB2 is the principal activator of

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