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MEK-1 Polyclonal Antibody, 50ul[BT-AP05342] ssDNA Synthesis Mutations in this gene are

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MEK-1 Polyclonal Antibody, 50ul[BT-AP05342] ssDNA Synthesis Mutations in this gene areThe protein encoded by MAP2K1 (mitogen activated protein kinase kinase 1) is a member of the dual specificity protein kinase family, which acts as a mitogen activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This protein kinase lies upstream of MAP kinases and stimulates the enzymatic activity of MAP kinases upon wide variety of

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Description

Mutations in this gene are a cause of familial persistent hyperinsulinemic hypoglycemia of infancy (PHHI)

MAP kinases are also known as extracellular signal-regulated kinases (ERKs)

The functional enzyme is thought to be a homodimer which uses FAD as a cofactor

rotein kinase which phosphorylates ESR1 (in vitro) and protects it against proteasomal degradation

Rare transcript variants have been reported for this gene

MEK-1 Polyclonal Antibody, 50ul[BT-AP05342] ssDNA Synthesis Mutations in this gene areThe protein encoded by MAP2K1 (mitogen activated protein kinase kinase 1) is a member of the dual specificity protein kinase family, which acts as a mitogen activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This protein kinase lies upstream of MAP kinases and stimulates the enzymatic activity of MAP kinases upon wide variety of

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