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120 Acetylation of PKM2 at the K433 site by acetyltransferase p300 leads to the accumulation of the dimeric form of PKM2 in the nucleus, functioning as a protein kinase, phosphorylating STAT3 and activating downstream signaling pathways

Depletion of RB1 in MDSCs has been shown to promote the growth of MDSC populations and inhibit their differentiation into mature myeloid cells such as neutrophils, monocytes, dendritic cells, and macrophages [104]

doi: 10.1111/j.1749-6632.1998.tb10696.x

Exogenous antioxidants as drugs Many polyphenolic compounds such as flavonoids, isoflavones, flavones, anthocyanins, coumarins, lignans, catechins, isocatechins, epicatechins, and phenolic acids have gained importance as antioxidant drugs

You might even have a diagnosis like Hashimotos or Rheumatoid Arthritis