PYGO2 Polyclonal Antibody, 20ul Lysosome this gene is disrupted in

this gene is disrupted in patients with CMT1A (Charcot-Marie-Tooth type 1A) duplication and with HNPP (hereditary neuropathy with liability to pressure palsies) deletion

CCNB1 and CDKN1A

noninsulin-dependent

The encoded protein plays a role in the early secretory pathway as a heterodimer with zinc transporter 6| and may also regulate zinc sequestration into secretory granules of pancreatic beta cells

However| the encoded protein does not appear to be a catalytically active phosphatase because it lacks several amino acids in the catalytic pocket

PYGO2 Polyclonal Antibody, 20ul Lysosome this gene is disrupted inInvolved in signal transduction through the Wnt pathway.,sequence Sequencing errors.,Contains 1 PHD type zinc finger.,subunit: Binds to BCL9 via the PHD type zinc finger motif, and thereby becomes part of the nuclear beta catenin TCF complex.,