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RNA-seq gene expression data were analysed using a negative binomial generalized linear model (DESeq2)

Natividad JM, Lamas B, Pham HP, Michel ML, Rainteau D, Bridonneau C, et al

Redox regulation of CRMP2 during development of the zebrafish brain requires activity of the vertebrate-specific Grx2 (Brutigam et al., In vitro analyses demonstrated a Cys504-Cys504 thiol-disulfide switch that determines distinct conformations of the homotetrameric protein (Gellert et al., 2 O 2 generation through the monooxygenase MICAL (Morinaka et al., 2011)

The following analyses will dissect the unique and shared metabolic features that disrupt T cell homeostasis in each disease, highlighting how immunological signals and metabolic pathways converge to dictate disease progression ( Table 1 )

One of the primary mechanisms through which IGF-1 LR3 promotes muscle hypertrophy is by stimulating protein synthesis