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In general, lyophilized peptide powder is first reconstituted into a compatible solution or mixed into a suitable topical base, then applied to clean skin or scalp

Ethics declarations Ethics approval and consent to participate Animal studies and procedures were carried out in accordance with an approved protocol from the Institutional Animal Care and Use Committee (IACUC) at the Fourth Military Medical University (IACUC-20220505)

Protect from light throughout handling

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At the clinical level, EDIT-101 is the first use of a genome editor in the CNS and is currently in phase 1/2 clinical trials in adult and pediatric patients ( Modified CRISPR activation Using the traditional CRISPR-Cas9 complex as a basis, a modified version in which the Cas9 enzyme is inactive or dead (dCas9) has been developed [64]